Flow Cytometry Analyzer Supplies
AdipoGen IL-33 ox-reshmonomer-KIH
Recombinant protein. Human IL-33 aa 112-270 with mutations C208S and C232S to protect IL-33 from oxidation is fused at the C-terminus to the Fc portion of human IgG1 Knobs-into-Holes technology see reference J.B. Ridgway, et al. Protein Eng. 9, 617 1996. Source HEK 293 cells. Lyophilized. Contains PBS Interleukin-33 IL-33 HF-NEV IL-1F11, a member of the IL-1 family of cytokines, is expressed by many cell types following pro-inflammatory stimulation and is thought to be released upon cell lysis. IL-33 binds to and signals through ST2 IL-1R1 and its stimulation recruits MYD88, IRAK, IRAK4 and TRAF6, followed by phosphorylation of ERK1 MAPK3 / ERK2 MAPK1, p38 MAPK14 and JNK. The ability of IL-33 to target numerous immune cell types, like Th2-like cells, mast cells and B1 cells, and to induce cytokine and chemokine production underlines its potential in influencing the outcome of a wide range of diseases, such as arthritis.
AdipoGen IL-38 aa20-152hmonom-KIH
Recombinant Protein. Human IL-38 aa 20-152 is fused at the C-terminus to the Fc portion of human IgG1 Knobs-into-Holes technology see reference J.B. Ridgway, et al. Protein Eng. 9, 617 1996. Source HEK 293 cells. Lyophilized. Contains PBS. IL-38 IL-1F10 belongs to the IL-1 family of proteins. IL-38 is expressed in heart, placenta, fetal liver, spleen, thymus and tonsil. The expression in a variety of immune tissues and similarity to IL-1Ra suggest a role of IL-38 in the inflammatory response. It has been reported that removal of the N-terminus domain of the interleukins of the IL-1F family such as IL-1F5 / 6 / 8 or 9 also called IL-36Ra, IL-36alpha, IL-36beta or IL-36gamma is important to increase their biological activity. Recently it has been shown that IL-38 is N-terminally processed and secreted by apoptotic cells.
AdipoGen IL-37 hmonomericFc-KIHh
Recombinant Protein. Human IL-37 aa 46-218 Delta5CysS-S and Y85A see reference A. Bujotzek, et al. 2022 is fused at the C-terminus to a Fc human IgG1 Knobs-into-Holes technology see reference J.B. Ridgway, et al. Protein Eng. 9, 617 1996. Source HEK 293 cells. Lyophilized. Contains PBS. IL-37 IL-1F7 IL-1H4 is an IL-1 family member that is expressed only in certain types of human organs and cells such as heart, thymus, testis, kidney, mononuclear cells PBMCs and dendritic cells. IL-37 is a soluble and secreted cytokine of 218 residues that shares the beta-trefoil fold common to IL-1 family cytokines. But IL-37 is an atypical member of the IL-1 family of cytokines as it functions to inhibit many of the major pathways of innate and adaptive immunity and inflammation. It binds to the interleukin-18 receptor IL-18R and its co-receptor SIGIRR.
AdipoGen IL-38 hrecHis MultiPack
Recombinant protein. Human IL-38 aa 1-152 is fused at the C-terminus to a His-tag. Source E. coli. Lyophilized. In 50mM TRIS-Cl, pH 8.0, containing 150mM NaCl. IL-38 IL-1F10 mRNA is expressed in heart, placenta, fetal liver, spleen, thymus and tonsil. The expression in a variety of immune tissues and similarity to IL-1Ra suggest a role of IL-1F10 in the inflammatory response. It has been reported that removal of the N-terminus domain of the interleukins of the IL-1F family such as IL-1F5 / 6 / 8 or 9 also called IL-36Ra, IL-36alpha, IL-36beta or IL-36gamma is important to increase their biological activity. Recently it has been shown that IL-38 is N-terminally processed and secreted by apoptotic cells. Released processed IL-38 20-152 binds to the receptor Interleukin-1 receptor accessory protein-like 1 IL1RAPL1 TIGIRR-2 at the surface of macrophages. Processed IL-38-activated IL1RAPL1 reduces the production of IL-6 leading to inflammation attenuation.
Revvity Health Sciences Inc AlphaScreen 6His Biotin Peptide, 10,000 Assay Points
AlphaScreen 6His Biotin Peptide, 10,000 Assay Points
Revvity Health Sciences Inc AlphaScreen pTyr-100 Detection Kit, 500 Assay Points
AlphaScreen pTyr-100 Detection Kit, 500 Assay Points
Revvity Health Sciences Inc PhenoVue Permeabilization 0.5% Triton X-100 Solution, 1x25mL
PhenoVue Permeabilization 0.5% Triton X-100 Solution, 1x25mL
Sigma Organic Chemistry EdU Flow Cytometry Kit 594
EdU Flow Cytometry Kit 594, EA
About This Item:
UNSPSC Code: 12352200
Storage: 2-8C
Sigma Organic Chemistry In Vivo EdU Click Kit 555
In Vivo EdU Click Kit 555, L
About This Item:
UNSPSC Code: 12352200
Storage: CL
Sigma Organic Chemistry EdU Flow Cytometry Kit 647
EdU Flow Cytometry Kit 647, EA
About This Item:
UNSPSC Code: 12352200
Storage: 2-8C
Sigma Organic Chemistry EdU Flow Cytometry Kit 555
EdU Flow Cytometry Kit 555, EA
About This Item:
UNSPSC Code: 12352200
Storage: 2-8C
Sigma Organic Chemistry EdU HTS Kit 488
EdU HTS Kit 488, EA
About This Item:
UNSPSC Code: 12352200
Storage: CL
Sigma Organic Chemistry In Vivo EdU Click Kit 555
In Vivo EdU Click Kit 555, IM
About This Item:
UNSPSC Code: 12352200
Storage: 2-8C